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Which Is Better For Muscle Growth, BCAA or Creatine?

Which Is Better For Muscle Growth, BCAA or Creatine?

There are two schools of thought regarding which is better for muscle building, BCAA or Creatine. Some people believe BCAA is the better option because it provides the body with the amino acids necessary to build muscle.

Creatine, on the other hand, helps to increase energy levels and improve athletic performance. So, which is the better option?

So, which is better for muscle building, BCAA or Creatine? In this post, we’ll look at the research on BCAA and Creatine and see which one comes out on top.

What is BCAA?

What is branch chain amino acid supplement

If you are trying to build muscle, then BCAA is the better choice. BCAA stands for branched-chain amino acids. These are the amino acids that are necessary for muscle growth. When you take BCAA supplements, you are providing your body with the building blocks it needs to build new muscle tissue.

What Does BCAA Do For Muscles?

What Does Branch Chain Amino Acid Do For Muscles

BCAA is a type of amino acid the body needs for muscle growth and repair. They are essential for building and maintaining muscle mass and play a role in fat metabolism. Athletes and bodybuilders often use BCAA supplements to help increase muscle mass and improve exercise performance. However, there is no scientific evidence to support these claims.

BCAA supplements are available in powder and capsule form. They can be taken before, after exercise, or consumed as part of a protein-rich diet.

There are no known side effects associated with taking BCAA supplements. However, people with liver or kidney disease should speak to their doctor before taking any supplement, as amino acids can be harmful in large amounts.

What Is Creatine?

Powder with scoop with chemical symbol carbamimidoyl-methyl-amino-acetic acid

Creatine is a naturally occurring organic compound with a formula (H2N)(HN)CN(CH3)CH2CO2H. Is a type of amino acid that is found in the body, and it helps to provide energy to the cells.

Creatine can be found in food sources such as meat and fish, and it can also be supplemented. This organic compound is better for increasing energy levels. It helps to replenish adenosine triphosphate(ATP) levels in the body.

Adenosine triphosphate(ATP) is the energy currency of the body. When ATP levels are low, you will feel tired and sluggish. Creatine can help to increase ATP levels, which can give you a boost of energy.

What Does Creatine Do To The Muscles?

What Does Créatine Monohydrate Do To The Muscles

When it is taken as a supplement, it helps to increase the levels of Creatine in the body, which can help to improve energy production and muscle function. The muscles also use it to help with contraction.

Creatine is a popular supplement among athletes and bodybuilders because it has been shown to improve performance. It helps increase ATP levels in the body, which is the primary energy source for muscles.

Creatine also helps to reduce the amount of lactic acid that builds up in the muscles during exercise, which can lead to fatigue. Additionally, Creatine can help to increase muscle mass and strength.

Most people who take creatine supplementation may not experience any side effects. However, some people may experience stomach upset, diarrhea, or nausea. Creatine should be taken with plenty of fluids to help reduce the risk of side effects.

People with kidney problems should not have creatine uptake supplements. If you are considering taking creatine supplements, talk to your doctor first to see if they are right for you.

What’s The Difference Between BCAAs and Creatine?

What’s The Difference Between BCAAs and Créatine Ethyl Ester

BCAA's are essential for muscle growth and recovery but don't provide energy. On the other hand, Creatine is a source of muscle energy. It allows them to work harder and longer before fatigue sets in.

So, Creatine is the way to go if you're looking for a supplement to help you perform better during your workouts. If you're more interested in building muscle and recovering from workouts, then BCAA's are the better choice. But there's no need to choose one over the other - both supplements can benefit athletes.

What are BCAA's Good For?

Like most people, you probably think of BCAA as just another supplement to take alongside your protein shake. But what if I told you that BCAA could actually help improve your performance in the gym and even help you lose weight? In this post, we’ll take a closer look at the benefits of BCAA and how they can help you achieve your fitness goals.

BCAA stands for branched-chain amino acids, a group of three essential amino acids: leucine, isoleucine, and valine. These amino acids are important because the body does not produce them, so we must get them through our diet. BCAA are found in foods like meat, poultry, and eggs but also in supplements.

Improves Performance

BCAA supplements have improved exercise performance by delaying fatigue and reducing muscle soreness. Studies show cyclists who took BCAA supplements before and during a race could ride further and faster than those who did not take BCAA. In another study, weightlifters who took BCAA supplements were able to increase their strength and reduce their muscle soreness.

Help With Lose Weight

BCAA supplements can also help you lose weight by increasing your metabolism and reducing your appetite. In one study, people who took BCAA supplements lost more weight and body fat than those who did not take BCAA. In another study, people who took BCAA supplements before and after exercise had a higher creatine metabolism for several hours after working out.

Increase Muscle Growth

BCAA supplements contain three essential amino acids: leucine, isoleucine, and valine. BCAA's are magical because they can be used pre-, during, and post-workout. They help to improve muscle strength, battle fatigue, and decrease recovery time.

Leucine is the most important of the three BCAAs for muscle growth. It works by switching on the protein synthesis machinery in your muscles. Think of leucine as the key that starts up the engine to make new muscle protein.

Isoleucine is important for endurance as it helps shuttle glucose and other nutrients into your muscles. Isoleucine also helps with protein synthesis, similar to leucine.

Valine is important for preventing muscle breakdown and helps with endogenous creatine synthesis. The supplementation appears to help you build lean muscle mass while burning fat. They are also incredibly cheap and cost-effective, so there is no excuse not to take them.

Decrease Muscle Soreness

A study by the International Society of Sports Nutrition concluded that BCAA could help reduce muscle soreness. Learning more from the joint international society of sports nutrition is essential for athletes because the less muscle soreness they experience, the more quickly they can recover and return to training.

The study found that older adults who took BCAA had less muscular dystrophy damage and soreness 24 hours after exercise and 48 hours after exercise compared to those who did not take BCAA. This indicates that BCAA can help reduce muscle soreness not only in the short term but also in the long term.

For athletes, this is vital because it means they can train more often and at a higher intensity without worrying about excessive muscle soreness. Consequently, they will see better results from their training.

Prevent Muscle Wasting

BCAAs are important for preventing muscle loss because they help to preserve muscle mass during times of caloric restriction. When you diet or fast, your body breaks down protein for energy. This results in muscle loss.

BCAAs can help prevent this by providing the body with an alternative energy source. Researchers found that people who were supplemented with BCAAs lost less muscle mass than those who did not supplement with BCAAs.

The Benefits Of Creatine

Creatine is one of the most popular supplements in the world, and for a good reason. It has many benefits that can improve your overall health, performance, and body composition. In this article, we’ll look at some of the main benefits of Creatine and how it can help you reach your fitness goals.

Improve strength

Creatine increases lean muscle mass, improves strength, and helps the muscles recover more quickly from exercise. Oral Creatine supplementation works by supplying energy to the muscles, which allows them to contract more forcefully. This can lead to improved strength and power during exercise.

Increase Lean Muscle Mass

Creatine is stored in the muscles in the form of creatine phosphate. During high-intensity exercise, creatine phosphate donates a phosphate group to AP (adenosine diphosphate), producing ATP (adenosine triphosphate) and resynthesizing ATP for energy production through a process called the phosphagen system.

For this to happen, you must have adequate muscle Creatine stores. Supplementing with Creatine can help increase muscle stores of creatine phosphate, leading to increased power output. Creatine has been shown to increase lean muscle mass, strength, and power.

Help The Muscles Recover More Quickly During Exercise

Creatine helps to supply energy to the muscles. Taking it as a supplement can increase the level of Creatine in the muscles, which has several benefits. For example, it can help the muscles recover more quickly during exercise, making it easier to stick to a workout regime.

It can also help to improve performance during short bursts of activity, such as sprinting. In addition, Creatine has been shown to reduce muscle fatigue, making it an important tool for athletes looking to improve their performance.

It Helps Muscle Cells Produce More Energy

Creatine is most effective when used in short bursts of high-intensity activity, such as sprinting or lifting weights. However, it can also be helpful for endurance athletes and those who participate in activities that require repeated short bursts of energy, such as football or basketball. Creatine is a safe and effective way to improve exercise performance and increase muscle mass and strength.

Improves High-Intensity Exercise Performance

Creatine is a nitrogenous organic compound that helps to supply energy to muscle cells. It can be taken as a dietary supplement to improve muscle mass and strength. Creatine has also improved high-intensity exercise performance, such as sprinting and weightlifting.

In one study, obese women supplemented with Creatine for eight weeks increased their lean body mass and improved their VO2 max (a measure of cardiorespiratory fitness). Whether you're looking to improve your athletic performance, Creatine may be worth considering.

Speeds Muscle Growth

Creatine has been shown to increase muscle mass and strength. It does this by increasing levels of ATP in the muscles. ATP is needed for muscle contraction.

When levels of ATP are increased, muscles can contract harder and for a longer period. This leads to an increase in muscle size and strength.

FAQs About BCAA And Creatine

FAQs about Awtsu Supplements

Should I Take BCAA Or Creatine?

Both supplements have pros and cons; ultimately, the best choice depends on your individual goals and needs. If you want to build muscle mass, then Creatine is the most effective option.

Creatine helps to increase energy production in cells, which leads to greater muscle growth. In addition, Creatine can help to reduce fatigue, making it easier to push yourself during workouts. On the other hand, if you are trying to lose weight, then BCAA may be the better choice.

BCAA helps to increase metabolism and burn fat, making it an ideal supplement for those trying to lose weight. In addition, BCAA can help to improve mental focus and reduce anxiety levels. So, if you are wondering which supplement is better for muscle building, it depends on your specific goals.

Will BCAAS Make My Muscles Bigger?

Yes! These amino acids are involved in muscle protein synthesis, which is the process that helps to repair and rebuild muscle tissue. BCAAs have been shown to stimulate muscle protein synthesis and promote the growth of new muscle fibers.

In one study, participants supplemented with BCAAs experienced increased muscle mass and strength after eight weeks of resistance training. Although more research is needed, these findings suggest that BCAAs could play a role in building bigger muscles.

So if you're looking to add a few extra pounds of muscle, you might consider adding some BCAAs to your supplement regimen.

Is Creatine And Creatine Monohydrate The Same?

Creatine is a popular supplement among athletes and bodybuilders. It's thought to improve performance and increase muscle mass. However, there is some debate as to whether it's effective. Creatine monohydrate is the most common form of Creatine.

It's also the cheapest and most researched form, with no significant adverse effects reported. So, if you're considering taking Creatine, it's probably best to stick with this form. That said, there is no evidence to suggest that other forms of Creatine are ineffective.

Will Creatine Make You Look Bigger?

Creatine is a naturally occurring substance that can cause your muscles to look bigger and stronger. Not only will you see an increase in size, but strength as well! You may notice these changes after just one week of supplementation. The longer we maintain our intake of Creatine or even if it's new for us - there could be some pretty amazing outcomes down the road.

What Is The Effect Of Creatine Supplementation?

Creatine is an amino acid that occurs naturally in skeletal muscle. It can also be synthesized in the liver, kidney, and pancreas. In skeletal muscle, creatine functions as an energy reservoir, providing phosphate groups that can be used during high-intensity exercise (1). Creatine supplementation combined has increased skeletal muscle creatine content and improved exercise performance (2-5).

In addition, creatine supplementation has been investigated as a potential therapy for various conditions, including traumatic brain injury and Alzheimer's Creatine kinase (6-8). However, more research is needed to determine the efficacy of creatine supplementation for these conditions.

Conclusion

So, what’s the verdict? Is BCAA better for muscle building than Creatine? In short, these two dietary supplements have their pros and cons. BCAA is excellent for helping you preserve muscle mass during a cut, while Creatine can help you achieve greater muscle size and strength gains.

However, I would recommend Creatine if you could only choose one supplement. It has been around longer, and more research is backing up its benefits. Plus, it’s generally cheaper than BCAA supplements.

If you want to start taking creatine supplements, I highly recommend checking the range of Awtsu supplements. Not only are their products high quality and effective, but they also have some of the best prices on the market. Give them a try today and see how they can help you reach your fitness goals!

References:

https://www.kidney.org

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126259/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021443/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241904/

https://www.hsph.harvard.edu/nutritionsource/workout-supplements/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183816/

https://www.huffinesinstitute.org

https://www.sciencedirect.com

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739317/

https://pubmed.ncbi.nlm.nih.gov/24620007/

There are two schools of thought regarding which is better for muscle building, BCAA or Creatine. Some people believe BCAA is the better option because it provides the body with the amino acids necessary to build muscle.

Creatine, on the other hand, helps to increase energy levels and improve athletic performance. So, which is the better option?

So, which is better for muscle building, BCAA or Creatine? In this post, we’ll look at the research on BCAA and Creatine and see which one comes out on top.

What is BCAA?

What is branch chain amino acid supplement

If you are trying to build muscle, then BCAA is the better choice. BCAA stands for branched-chain amino acids. These are the amino acids that are necessary for muscle growth. When you take BCAA supplements, you are providing your body with the building blocks it needs to build new muscle tissue.

What Does BCAA Do For Muscles?

What Does Branch Chain Amino Acid Do For Muscles

BCAA is a type of amino acid the body needs for muscle growth and repair. They are essential for building and maintaining muscle mass and play a role in fat metabolism. Athletes and bodybuilders often use BCAA supplements to help increase muscle mass and improve exercise performance. However, there is no scientific evidence to support these claims.

BCAA supplements are available in powder and capsule form. They can be taken before, after exercise, or consumed as part of a protein-rich diet.

There are no known side effects associated with taking BCAA supplements. However, people with liver or kidney disease should speak to their doctor before taking any supplement, as amino acids can be harmful in large amounts.

What Is Creatine?

Powder with scoop with chemical symbol carbamimidoyl-methyl-amino-acetic acid

Creatine is a naturally occurring organic compound with a formula (H2N)(HN)CN(CH3)CH2CO2H. Is a type of amino acid that is found in the body, and it helps to provide energy to the cells.

Creatine can be found in food sources such as meat and fish, and it can also be supplemented. This organic compound is better for increasing energy levels. It helps to replenish adenosine triphosphate(ATP) levels in the body.

Adenosine triphosphate(ATP) is the energy currency of the body. When ATP levels are low, you will feel tired and sluggish. Creatine can help to increase ATP levels, which can give you a boost of energy.

What Does Creatine Do To The Muscles?

What Does Créatine Monohydrate Do To The Muscles

When it is taken as a supplement, it helps to increase the levels of Creatine in the body, which can help to improve energy production and muscle function. The muscles also use it to help with contraction.

Creatine is a popular supplement among athletes and bodybuilders because it has been shown to improve performance. It helps increase ATP levels in the body, which is the primary energy source for muscles.

Creatine also helps to reduce the amount of lactic acid that builds up in the muscles during exercise, which can lead to fatigue. Additionally, Creatine can help to increase muscle mass and strength.

Most people who take creatine supplementation may not experience any side effects. However, some people may experience stomach upset, diarrhea, or nausea. Creatine should be taken with plenty of fluids to help reduce the risk of side effects.

People with kidney problems should not have creatine uptake supplements. If you are considering taking creatine supplements, talk to your doctor first to see if they are right for you.

What’s The Difference Between BCAAs and Creatine?

What’s The Difference Between BCAAs and Créatine Ethyl Ester

BCAA's are essential for muscle growth and recovery but don't provide energy. On the other hand, Creatine is a source of muscle energy. It allows them to work harder and longer before fatigue sets in.

So, Creatine is the way to go if you're looking for a supplement to help you perform better during your workouts. If you're more interested in building muscle and recovering from workouts, then BCAA's are the better choice. But there's no need to choose one over the other - both supplements can benefit athletes.

What are BCAA's Good For?

Like most people, you probably think of BCAA as just another supplement to take alongside your protein shake. But what if I told you that BCAA could actually help improve your performance in the gym and even help you lose weight? In this post, we’ll take a closer look at the benefits of BCAA and how they can help you achieve your fitness goals.

BCAA stands for branched-chain amino acids, a group of three essential amino acids: leucine, isoleucine, and valine. These amino acids are important because the body does not produce them, so we must get them through our diet. BCAA are found in foods like meat, poultry, and eggs but also in supplements.

Improves Performance

BCAA supplements have improved exercise performance by delaying fatigue and reducing muscle soreness. Studies show cyclists who took BCAA supplements before and during a race could ride further and faster than those who did not take BCAA. In another study, weightlifters who took BCAA supplements were able to increase their strength and reduce their muscle soreness.

Help With Lose Weight

BCAA supplements can also help you lose weight by increasing your metabolism and reducing your appetite. In one study, people who took BCAA supplements lost more weight and body fat than those who did not take BCAA. In another study, people who took BCAA supplements before and after exercise had a higher creatine metabolism for several hours after working out.

Increase Muscle Growth

BCAA supplements contain three essential amino acids: leucine, isoleucine, and valine. BCAA's are magical because they can be used pre-, during, and post-workout. They help to improve muscle strength, battle fatigue, and decrease recovery time.

Leucine is the most important of the three BCAAs for muscle growth. It works by switching on the protein synthesis machinery in your muscles. Think of leucine as the key that starts up the engine to make new muscle protein.

Isoleucine is important for endurance as it helps shuttle glucose and other nutrients into your muscles. Isoleucine also helps with protein synthesis, similar to leucine.

Valine is important for preventing muscle breakdown and helps with endogenous creatine synthesis. The supplementation appears to help you build lean muscle mass while burning fat. They are also incredibly cheap and cost-effective, so there is no excuse not to take them.

Decrease Muscle Soreness

A study by the International Society of Sports Nutrition concluded that BCAA could help reduce muscle soreness. Learning more from the joint international society of sports nutrition is essential for athletes because the less muscle soreness they experience, the more quickly they can recover and return to training.

The study found that older adults who took BCAA had less muscular dystrophy damage and soreness 24 hours after exercise and 48 hours after exercise compared to those who did not take BCAA. This indicates that BCAA can help reduce muscle soreness not only in the short term but also in the long term.

For athletes, this is vital because it means they can train more often and at a higher intensity without worrying about excessive muscle soreness. Consequently, they will see better results from their training.

Prevent Muscle Wasting

BCAAs are important for preventing muscle loss because they help to preserve muscle mass during times of caloric restriction. When you diet or fast, your body breaks down protein for energy. This results in muscle loss.

BCAAs can help prevent this by providing the body with an alternative energy source. Researchers found that people who were supplemented with BCAAs lost less muscle mass than those who did not supplement with BCAAs.

The Benefits Of Creatine

Creatine is one of the most popular supplements in the world, and for a good reason. It has many benefits that can improve your overall health, performance, and body composition. In this article, we’ll look at some of the main benefits of Creatine and how it can help you reach your fitness goals.

Improve strength

Creatine increases lean muscle mass, improves strength, and helps the muscles recover more quickly from exercise. Oral Creatine supplementation works by supplying energy to the muscles, which allows them to contract more forcefully. This can lead to improved strength and power during exercise.

Increase Lean Muscle Mass

Creatine is stored in the muscles in the form of creatine phosphate. During high-intensity exercise, creatine phosphate donates a phosphate group to AP (adenosine diphosphate), producing ATP (adenosine triphosphate) and resynthesizing ATP for energy production through a process called the phosphagen system.

For this to happen, you must have adequate muscle Creatine stores. Supplementing with Creatine can help increase muscle stores of creatine phosphate, leading to increased power output. Creatine has been shown to increase lean muscle mass, strength, and power.

Help The Muscles Recover More Quickly During Exercise

Creatine helps to supply energy to the muscles. Taking it as a supplement can increase the level of Creatine in the muscles, which has several benefits. For example, it can help the muscles recover more quickly during exercise, making it easier to stick to a workout regime.

It can also help to improve performance during short bursts of activity, such as sprinting. In addition, Creatine has been shown to reduce muscle fatigue, making it an important tool for athletes looking to improve their performance.

It Helps Muscle Cells Produce More Energy

Creatine is most effective when used in short bursts of high-intensity activity, such as sprinting or lifting weights. However, it can also be helpful for endurance athletes and those who participate in activities that require repeated short bursts of energy, such as football or basketball. Creatine is a safe and effective way to improve exercise performance and increase muscle mass and strength.

Improves High-Intensity Exercise Performance

Creatine is a nitrogenous organic compound that helps to supply energy to muscle cells. It can be taken as a dietary supplement to improve muscle mass and strength. Creatine has also improved high-intensity exercise performance, such as sprinting and weightlifting.

In one study, obese women supplemented with Creatine for eight weeks increased their lean body mass and improved their VO2 max (a measure of cardiorespiratory fitness). Whether you're looking to improve your athletic performance, Creatine may be worth considering.

Speeds Muscle Growth

Creatine has been shown to increase muscle mass and strength. It does this by increasing levels of ATP in the muscles. ATP is needed for muscle contraction.

When levels of ATP are increased, muscles can contract harder and for a longer period. This leads to an increase in muscle size and strength.

FAQs About BCAA And Creatine

FAQs about Awtsu Supplements

Should I Take BCAA Or Creatine?

Both supplements have pros and cons; ultimately, the best choice depends on your individual goals and needs. If you want to build muscle mass, then Creatine is the most effective option.

Creatine helps to increase energy production in cells, which leads to greater muscle growth. In addition, Creatine can help to reduce fatigue, making it easier to push yourself during workouts. On the other hand, if you are trying to lose weight, then BCAA may be the better choice.

BCAA helps to increase metabolism and burn fat, making it an ideal supplement for those trying to lose weight. In addition, BCAA can help to improve mental focus and reduce anxiety levels. So, if you are wondering which supplement is better for muscle building, it depends on your specific goals.

Will BCAAS Make My Muscles Bigger?

Yes! These amino acids are involved in muscle protein synthesis, which is the process that helps to repair and rebuild muscle tissue. BCAAs have been shown to stimulate muscle protein synthesis and promote the growth of new muscle fibers.

In one study, participants supplemented with BCAAs experienced increased muscle mass and strength after eight weeks of resistance training. Although more research is needed, these findings suggest that BCAAs could play a role in building bigger muscles.

So if you're looking to add a few extra pounds of muscle, you might consider adding some BCAAs to your supplement regimen.

Is Creatine And Creatine Monohydrate The Same?

Creatine is a popular supplement among athletes and bodybuilders. It's thought to improve performance and increase muscle mass. However, there is some debate as to whether it's effective. Creatine monohydrate is the most common form of Creatine.

It's also the cheapest and most researched form, with no significant adverse effects reported. So, if you're considering taking Creatine, it's probably best to stick with this form. That said, there is no evidence to suggest that other forms of Creatine are ineffective.

Will Creatine Make You Look Bigger?

Creatine is a naturally occurring substance that can cause your muscles to look bigger and stronger. Not only will you see an increase in size, but strength as well! You may notice these changes after just one week of supplementation. The longer we maintain our intake of Creatine or even if it's new for us - there could be some pretty amazing outcomes down the road.

What Is The Effect Of Creatine Supplementation?

Creatine is an amino acid that occurs naturally in skeletal muscle. It can also be synthesized in the liver, kidney, and pancreas. In skeletal muscle, creatine functions as an energy reservoir, providing phosphate groups that can be used during high-intensity exercise (1). Creatine supplementation combined has increased skeletal muscle creatine content and improved exercise performance (2-5).

In addition, creatine supplementation has been investigated as a potential therapy for various conditions, including traumatic brain injury and Alzheimer's Creatine kinase (6-8). However, more research is needed to determine the efficacy of creatine supplementation for these conditions.

Conclusion

So, what’s the verdict? Is BCAA better for muscle building than Creatine? In short, these two dietary supplements have their pros and cons. BCAA is excellent for helping you preserve muscle mass during a cut, while Creatine can help you achieve greater muscle size and strength gains.

However, I would recommend Creatine if you could only choose one supplement. It has been around longer, and more research is backing up its benefits. Plus, it’s generally cheaper than BCAA supplements.

If you want to start taking creatine supplements, I highly recommend checking the range of Awtsu supplements. Not only are their products high quality and effective, but they also have some of the best prices on the market. Give them a try today and see how they can help you reach your fitness goals!

References:

https://www.kidney.org

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126259/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021443/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241904/

https://www.hsph.harvard.edu/nutritionsource/workout-supplements/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183816/

https://www.huffinesinstitute.org

https://www.sciencedirect.com

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739317/

https://pubmed.ncbi.nlm.nih.gov/24620007/

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